NETWORKING RESOURCE CENTRE IN BIOLOGICAL SCIENCES

INVESTIGATOR'S PROFILE

Dr. A. MAHESH, Ph. D.,

Project Faculty
DBT- IPLS Program
School Of Biological Sciences,
Madurai Kamaraj University,
Madurai-625021,
Tamil Nadu, India.
Mobile: +91-98438 74873
E mail: mahesh.a@dbtiplsmku.org;
mahesh.a06@gmail.com

Professional Experience:

Faculty in the School of Biological Sciences, Madurai Kamaraj University,

Madurai- 625021. (Sep 2011 onwards)

Post Doctoral Scientist, The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel. (July 2011- Sep 2011)
Post Doctoral Scientist, Department of Plant Genetics, Agricultural Research Organization, The Volcani Centre, Bet-Dagan 50250, Israel. (Jan 2009-June 2011)

Honors and Awards

Konan Zoref Post- doc fellowship, Bar-Ilan University, Ramat- Gan, Israel (2011-2012)
University Research Fellow, Bharathidasan University, Tiruchirapalli, India (2005-2008)
Reviewer, Journal of Journal of Pharmacy and Pharmacology, Wiley-Blackwell Publications (Since 2010)
Reviewer, Pharmaceutical Biology, Taylor & Francis Publications (Since 2008)
Reviewer, Natural Product research, Wiley-Blackwell Publications (Since 2010)
Associate Editor, Biotechnology, Asian Network for Scientific Information (2007-2011)
Associate Editor, International Journal of Pharmacology, Asian Network for Scientific Information (2007-2011)

Area of Interest

Plant Genetic Engineering.
Drug Development and Delivery
Toxicology

PUBLICATIONS
Journals

Mahesh, A., Levy, Y., Gaba, V. and Gafni, Y. 2011. Biolistic transformation of tobacco plants using Rolling Circle Amplification (RCA) DNA product. (In preparation).
Mahesh, A., Levy, Y., and Gafni, Y. 2011. Production of siRNA targeted against the Ricin protein transcripts leads to inhibition of its expression in tobacco plants. (In preparation).
Mahesh, A. and Gobinath, S. Biotechnology and Traditional Medicines- Invited review. Afr. J. Trad. CAM, (Under review).
Gobinath, S., Mahesh, A., Thangadurai, D. and Muralidhara Rao, D. Effect of flavonoids and polyphenols of Cassia auriculata. L. on cisplatin induced nephrotoxicity in rats. Experimental and Toxicologic Pathology, (Under review).
Mahesh, A., Jeyachandran, R., Muralidhara Rao, D. and Thangadurai, D. Gastroprotective effects of Desmodium gangeticum root extracts on ethanol induced gastric mucosal injury in experimental mice. Natural Product Research, (Revised submitted).
Sathish Climer, C., Mahesh, A., Sinilal, B., Muralidhara Rao, D. and Thangadurai, D. Protective effect of Indigofera aspalathoides roots on N-nitrosodiethylamine induced hepatocarcinogenesis in mice. Indian Journal of Pharmaceutical Sciences. (Revised submitted).
Mahesh, A. and Jeyachandran, R. Influence of plant growth regulators on in vitro flowering of Trichodesma indicum (Linn.) R. Br. Plant biosystems, (Revised submitted).
Vimaladevi, S., Mahesh, A., Dhayanithi, N.B. and Karthikeyan, N. Mosquito larvicidal efficacy of phenolic acids of seaweed Chaetomorpha antennina (Bory) Kuetz. Biologia. (Revised submitted).
Mahesh, A., Thangadurai, D. and Melchias, G. (2011). Rapid in vitro plant regeneration from leaf explants of Launaea sarmentosa (Willd.) Schult- Bip. Biological Research, (Accepted).
Gobinath, S., Mahesh, A., Thangadurai, D. and Muralidhara Rao, D. (2011). Protective effect of Caralluma umbellate Haw. against paracetamol induced oxidative stress and hepatotoxicity in rat. Acta Biologica Hungarica. (Accepted).
Mahesh, A. and Jeyachandran, R. (2011). Agrobacterium rhizogenes-mediated hairy root induction in Taraxacum officinale and analysis of sesquiterpene lactones. Plant biosystems, 145: 620-626.
Mahesh, A., Jeyachandran, R., Cindrella, L., Thangadurai, D. and Muralidhara Rao, D. (2010). Hepatocurative potential of sesquiterpene lactones of Taraxacum officinale on carbon tetrachloride induced liver toxicity in mice. Acta Biologica Hungarica, 61(2): 175–190.
Mahesh, A., Shaheetha, J., Thangadurai, D. and Muralidhara Rao, D. (2009). Protective effect of Indian honey on acetaminophen induced oxidative stress and liver toxicity in rat. Biologia, 64(6): 1225-1231.
Jeyachandran, R., Mahesh, A., Cindrella, L., Sudhakar, S. and Pazhanichamy, K. (2009). Evaluation of antibacterial activity of plumbagin and the root extracts of Plumbago zeylanica L. Acta Biologica Cracoviensia Series Botanica, 51(1): 17–22.
Jeyachandran, R. and Mahesh, A. (2007). Agrobacterium rhizogenes mediated hairy root induction in Oxystelma esculentum (L.f). R. Br. Journal of Biological Research, 8: 207- 212.
Jeyachandran, R., Mahesh, A. and Cindrella, L. (2007). DEN - induced cancer and its alleviation by Anisomeles malabarica (L.) R. Br. ethanolic leaf extract in male albino mice. International Journal of Cancer Research, 3(4): 174-179.
Mahesh, A. and Jeyachandran, R. (2005). Regeneration of Taraxacum officinale through nodal explants. J. Trop. Med. Plants, 6(2), 245-248.

BOOK CHAPTERS

Mahesh, A. and Thangadurai, D. Transformed hairy root induction: a tool for enhancement of secondary metabolites in Taraxacum officinale. In: Thangadurai et al., (eds), Molecular Agrobiology, (Accepted)
Jeyachandran, R., Mahesh, A. and Cindrella, L. (2010). Glucosamine- a novel medicine for Arthritis. In: Role of Biotechnology in Medicinal and Aromatic plants, Vol- XXI, Ali Khan, I. and khanum, A (eds). Ukaaz publications, Hyderabad. 246-272
Jeyachandran, R., Mahesh, A. and Cindrella, L. (2010). Epidemiology of Hot water epilepsy. In: Role of Biotechnology in Medicinal and Aromatic plants, Vol- XXI, Ali Khan, I. and khanum, A (eds). Ukaaz publications, Hyderabad. Pp 273-296
Mahesh, A., Jeyachandran, R., Cindrella, L. Thangadurai, D. and Pinheiro de Carvalho, M.A.A. (2008). Phytochemical, Pharmacological and Tissue Culture Studies on Taraxacum officinale Weber (Asteraceae). In: Biotechnology for food, Environment and Agriculture, Vol. I. Thangadurai, D. (eds.), Agrobios Press, India. pp. 235-251.
Jeyachandran, R., Mahesh, A. and Cindrella, L. (2008). Hepatoprotective Medicines, In: Role of Biotechnology in Medicinal and Aromatic plants, Vol- XIX. Ali Khan, I., Khanum, A. and Ahad khan, A. (eds). Ukaaz publications, Hyderabad. pp 114-142.
Jeyachandran, R., Mahesh, A. and Cindrella, L. (2008). Nephroprotective Plant Medcines, In: Role of Biotechnology in Medicinal and Aromatic plants, Vol- XIX. Ali Khan, I., Khanum, A. and Ahad khan, A. (eds). Ukaaz publications, Hyderabad. pp 143-168.
Jeyachandran, R., Mahesh, A., Krithika, G and Cindrella, L. (2008). Immunotoxicology, In: Role of Biotechnology in Medicinal and Aromatic, Vol- XX. Ali Khan, I., Khanum, A. and Ahad khan, A. (eds). Ukaaz publications, Hyderabad. pp 262-290.
Jeyachandran, R., Mahesh, A. and Cindrella, L. (2008). Pathogenesis of Poliomyelitis. In: Herbal Medicine for Human Diseases, Vol- IV. Ali Khan, I. and khanum, A. (eds). Ukaaz publications, Hyderabad. pp 271-296.

PRESENTATIONS IN CONFERENCES: (Selected)
Total No. Published: 46

Jeyachandran R, and Mahesh A. (2005). Hepatoprotective and antimalarial property of Calycoptoris floribunda Lam., Proceedings of National level Seminar on Chemistry in health and nutrition, organized by Departments of Chemistry & Biochemistry, Theivanai Ammal College for Women, Villupuram, 3rd October 2005.
Jeyachandran R, and Mahesh A. (2006). Cocculus hirsutus (L.) Diols –a potential antigonorhoea and antihypertensive drug, Proceedings of National Seminar on human perspective of Biotechnology organized by School of Biosciences, Mahendra Arts and Science College, Kalippatti, Namakkal 11th & 12th February 2006.
Jeyachandran R, and Mahesh A (2006). In vitro micropropagation of Cocculus hirsutus (L.) Diols through nodal explant, Proceedings of National Seminar on Advances in Plant Science organized by Department of Plant Science, Bharadhidasan University, Tiruchirappalli, 24th & 25th February 2006.
Jeyachandran, R., Mahesh, A. and Devi, A. (2006). A suitable protocol for the Micropropagation of Oxystelma esculentum (L.f.) R.Br. One day National Seminar on Thrust Areas in Biotechnology. Organized by Department of Biotechnology. Bishop Heber College. Tiruchirappalli. Sep 19.
Jeyachandran, R., Sindhu, K.K. and Mahesh, A. (2006). Indigofera aspalathoides- as effective medicine for sexually transmitted diseases. State level Seminar on Tribals, Forests and Futures. Organized by Centre for Future Study. Gandhigram Rural University. Dindigul. Dec 11.
Jeyachandran, R., Vincy, S. and Mahesh, A. (2007). Evaluation of pharmacological properties of Argemone maxicana. National Seminar on New Frontiers in Biological Science. Organized by Department of Botany. Holy Cross College. Tiruchirappalli. Jan 19-20.
Jeyachandran, R. and Mahesh, A. (2007). Agrobacterium rhizogenes (Strain No. 15834) induced gene transfer in Oxystelma esculentum (L.f) R. Br. International Conference on “Opportunities and Challenges in Biotechnology and Environmental Science”. Organized by Department of Botany. Vellalar College for Women. Erode. Feb 22-23.
Jeyachandran, R., and Mahesh, A. (2007). Hepatoprotective role of Oxystelma esculentum (L) RBr. National Seminar on Emerging Trends of Biotechnology in the medicinal plant. Organized by Department of Zoology. Nirmala College for women. Coimbatore. Feb 27-28.
Jeyachandran, R., Mahesh, A. and Sathish Climer, C. (2007). Anticancerous property of Indigofera aspalathoides. National Seminar on Emerging Trends of Biotechnology in the medicinal plant. Organized by Department of Zoology. Nirmala College for women. Coimbatore. Feb 27-28.
Jeyachandran, R., Meenakshi, C. T., Mahesh, A., Gobinath, S. and Cindrella L. (2008). Phytopharmaceutical Significance of Psoralea corylifolia L. National Symposium on Sustainable Utilization and Conservation of Medicinal Plants. Organized by Department of Plant Biology and Plant Biotechnology. Nirmala College for Women. Coimbatore. August 21st and 22nd.
Jeyachandran R, and Mahesh A. (2005). Hepatoprotective and antimalarial property of Calycoptoris floribunda Lam., Proceedings of National level Seminar on Chemistry in health and nutrition, organized by Departments of Chemistry & Biochemistry, Theivanai Ammal College for Women, Villupuram, 3rd October 2005.
Jeyachandran R, and Mahesh A. (2006). Cocculus hirsutus (L.) Diols –a potential antigonorhoea and antihypertensive drug, Proceedings of National Seminar on human perspective of Biotechnology organized by School of Biosciences, Mahendra Arts and Science College, Kalippatti, Namakkal 11th & 12th February 2006.
Jeyachandran R, and Mahesh A (2006). In vitro micropropagation of Cocculus hirsutus (L.) Diols through nodal explant, Proceedings of National Seminar on Advances in Plant Science organized by Department of Plant Science, Bharadhidasan University, Tiruchirappalli, 24th & 25th February 2006.
Jeyachandran, R., Mahesh, A. and Devi, A. (2006). A suitable protocol for the Micropropagation of Oxystelma esculentum (L.f.) R.Br. One day National Seminar on Thrust Areas in Biotechnology. Organized by Department of Biotechnology. Bishop Heber College. Tiruchirappalli. Sep 19.
Jeyachandran, R., Sindhu, K.K. and Mahesh, A. (2006). Indigofera aspalathoides- as effective medicine for sexually transmitted diseases. State level Seminar on Tribals, Forests and Futures. Organized by Centre for Future Study. Gandhigram Rural University. Dindigul. Dec 11.
Jeyachandran, R., Vincy, S. and Mahesh, A. (2007). Evaluation of pharmacological properties of Argemone maxicana. National Seminar on New Frontiers in Biological Science. Organized by Department of Botany. Holy Cross College. Tiruchirappalli. Jan 19-20.
Jeyachandran, R. and Mahesh, A. (2007). Agrobacterium rhizogenes (Strain No. 15834) induced gene transfer in Oxystelma esculentum (L.f) R. Br. International Conference on “Opportunities and Challenges in Biotechnology and Environmental Science”. Organized by Department of Botany. Vellalar College for Women. Erode. Feb 22-23.
Jeyachandran, R., and Mahesh, A. (2007). Hepatoprotective role of Oxystelma esculentum (L) RBr. National Seminar on Emerging Trends of Biotechnology in the medicinal plant. Organized by Department of Zoology. Nirmala College for women. Coimbatore. Feb 27-28.
Jeyachandran, R., Mahesh, A. and Sathish Climer, C. (2007). Anticancerous property of Indigofera aspalathoides. National Seminar on Emerging Trends of Biotechnology in the medicinal plant. Organized by Department of Zoology. Nirmala College for women. Coimbatore. Feb 27-28.
Jeyachandran, R., Meenakshi, C. T., Mahesh, A., Gobinath, S. and Cindrella L. (2008). Phytopharmaceutical Significance of Psoralea corylifolia L. National Symposium on Sustainable Utilization and Conservation of Medicinal Plants. Organized by Department of Plant Biology and Plant Biotechnology. Nirmala College for Women. Coimbatore. August 21st and 22nd.